Trisequens

Licensed Doctors
24-48h delivery
Secure Service
How to Order
Choose treatment
Select your option
Online consultation
Doctor reviews
Delivered home
Within 24-48h
Includes online consultation
Includes discreet delivery
Original medication
Treatment only prescribed if clinically appropriate.
Important: Prescriptsy connects you with independent, EU-registered doctors. We do not sell medication directly. All treatments are prescribed by a doctor and delivered discreetly to your door.
Order Trisequens without your own prescription
Prescriptsy helps you obtain Trisequens through reliable online healthcare providers. The process is simple: complete a consultation, a doctor reviews your request, and upon approval you receive Trisequens at home.
About This Treatment
What is Trisequens and How Does It Work?
Trisequens is a sequential Hormone Replacement Therapy (HRT) specifically designed for women who are experiencing symptoms of the menopause and still have an intact uterus. As the body transitions through menopause, the production of the hormone oestrogen declines, which can lead to a variety of uncomfortable physical and emotional symptoms. Trisequens works by supplementing the body with oestradiol (a natural oestrogen) to alleviate these symptoms.
Unlike continuous combined HRT, Trisequens is a three-phase treatment that mimics the natural female menstrual cycle. Each 28-day pack contains three different types of tablets: oestrogen-only tablets, followed by tablets containing both oestrogen and a progestogen (norethisterone acetate), and finally, a lower dose of oestrogen. The addition of progestogen is vital for women with a uterus, as it protects the lining of the womb (endometrium) from the overgrowth that can be caused by oestrogen alone. If you are looking to manage your symptoms effectively, you can buy Trisequens online via Prescriptsy following a successful clinical review.
Benefits of Choosing Trisequens for Menopause Management
Choosing Trisequens through Prescriptsy ensures you receive genuine medication from an EU-regulated pharmacy. This treatment is now available through online consultation, providing a discreet and professional way to manage menopausal health without the need for an in-person appointment.
- Comprehensive Symptom Relief: Highly effective at reducing hot flushes, night sweats, vaginal dryness, and sleep disturbances.
- Bone Protection: Helps prevent the loss of bone density (osteoporosis) that often occurs after menopause, reducing the risk of fractures.
- Predictable Cycle: As a sequential HRT, it usually results in a regular monthly withdrawal bleed, which is often preferred by women in the early stages of menopause.
- Convenience and Privacy: Prescriptsy offers a streamlined process where your medical history is reviewed by EU-licensed doctors, with medication delivered in discrete packaging to your door.
- Quality Assurance: We only provide genuine, UK and EU-approved medications, ensuring the highest standards of safety and efficacy.
How to Take Trisequens Properly
To ensure maximum efficacy and safety, Trisequens must be taken exactly as directed by your doctor. The medication comes in a calendar dial pack containing 84 tablets (enough for three cycles), designed to help you stay on track with the sequential phases.
The standard dosage is one tablet taken daily, preferably at the same time each day, without a break between packs. The cycle follows a specific order:
- Blue tablets (Days 1-12): Contain only oestradiol.
- White tablets (Days 13-22): Contain both oestradiol and norethisterone acetate.
- Red tablets (Days 23-28): Contain a lower dose of oestradiol.
You should swallow the tablets whole with a drink of water. If you forget to take a dose, take it as soon as you remember, unless it is more than 12 hours late. If more than 12 hours have passed, skip the missed dose and continue with the next scheduled tablet. Do not take a double dose to make up for a forgotten one.
Possible Side Effects
While Trisequens is a safe and effective treatment for many, it is a prescription-only medication that requires a medical assessment to ensure it is appropriate for you. During your online consultation, it is essential to provide a full medical history.
Contraindications
Trisequens should not be used if you have or have ever had:
- Breast cancer or any oestrogen-sensitive cancer.
- Unexplained vaginal bleeding.
- Blood clots (thrombosis) or a blood-clotting disorder.
- A recent heart attack or stroke.
- Active liver disease.
- Porphyria (a rare blood disease).
Potential Side Effects
Like all medications, Trisequens can cause side effects, although not everyone will experience them. Common side effects may include:
- Breast tenderness or enlargement.
- Headaches or migraines.
- Fluid retention and bloating.
- Nausea or abdominal pain.
- Breakthrough bleeding or spotting during the first few months of treatment.
- Mood changes or anxiety.
HRT is associated with a slightly increased risk of blood clots, stroke, and certain types of cancer (such as breast cancer) when used long-term. Your prescribing doctor will discuss these risks with you to ensure that the benefits of treatment outweigh the potential risks in your specific case. Regular check-ups and breast screenings are recommended while taking any form of HRT.
Trisequens buy with online consultation
Trisequens is a prescription-only medicine in the UK and most EU countries This means you cannot simply buy it without a prescription.
However, via an online consultation you do not need to visit your own GP. The process works as follows:
- Click 'Go to partner service' – We have found the most reliable partner who can offer this medication safely and discreetly.
- Fill out questionnaire at partner – Fill out a medical questionnaire with our partner
- Doctor review – An EU-registered doctor reviews your request
- Discreet delivery – Upon approval you receive Trisequens discreetly delivered to your home
Important: Prescriptsy does not sell medication itself. We independently compare trusted partners with EU-registered doctors, so you can make a safe and legal choice.
Medically reviewed by
Dr. Claire Phipps is an experienced General Practitioner with many years of experience in the NHS. She reviews all medical content on this page to ensure accuracy and reliability.
Related Treatments

Evra Patches

Estraderm Mx

Cerazette
Cerazette is a progestogen-only pill, also known as the mini-pill. It is used by women to prevent pregnancy. Unlike combined oral contraceptives, Cerazette does not contain any oestrogen.Cerazette contains a small amount of one type of female sex hormone, the progestogen desogestrel. Because of this

Dianette Diane
Dianette Diane is a combined oral contraceptive pill used to treat severe acne in women who also require contraception. It contains cyproterone acetate (an anti-androgen) and ethinylestradiol (an oestrogen). This medication is now available through online consultation with a GMC-registered doctor.
Includes online consultation
Includes discreet delivery
Original medication
Treatment only prescribed if clinically appropriate.
Important: Prescriptsy connects you with independent, EU-registered doctors. We do not sell medication directly. All treatments are prescribed by a doctor and delivered discreetly to your door.
