Everything about Antihistamines
Antihistamines are a class of medication used to treat symptoms of allergies, such as hay fever, hives, and reactions to insect bites. They work by blocking histamine, a chemical released by the immune system during an allergic reaction.
Modern vs. Traditional Antihistamines
- Second and Third Generation: Medications like Fexofenadine (Telfast), Desloratadine, and Cetirizine are the preferred choice for most adults as they provide effective relief without causing drowsiness.
- First Generation: Older medications like Phenergan (Promethazine) or Hydroxyzine can cause significant sleepiness and are sometimes used when an allergy also affects sleep.
Commonly Treated Symptoms
- Constant sneezing and a runny or itchy nose.
- Itchy, watery, or red eyes.
- Hives and itchy skin rashes.
- Swelling caused by insect stings or bites.
Available Formulations
- Oral Tablets: The most common way to take antihistamines for systemic symptom control.
- Nasal Sprays: Like Rhinolast (Azelastine) or the combination spray Dymista, which provide rapid relief directly where needed.
- Eye Drops: Opatanol and Zaditen target localized itching and redness in the eyes.
Choosing the Right Option
Your choice of antihistamine should depend on your primary symptoms and how they affect your daily life. For those who need to remain alert for driving or work, modern non-drowsy versions are essential.
Consult with a UK Clinician Online
If over-the-counter antihistamines are not providing sufficient relief, our doctors can prescribe clinical-strength options. Complete an online consultation today for expert review and discreet delivery from our registered UK pharmacy.












