GP Guide to Managing IBS
Available treatment options
Treatment for IBS is never one-size-fits-all, but for sudden, painful abdominal cramps, I typically recommend starting with an antispasmodic. Colofac (containing the active ingredient mebeverine) is a staple in my prescribing arsenal.
It works directly on the smooth muscle of the bowel to relax the spasm without paralyzing normal gut motility. Unlike some older painkillers or opioid-based medications, it won't cause rebound constipation, which is absolutely crucial for patients who suffer from mixed-type IBS (alternating between diarrhea and constipation).
What to expect from treatment
Antispasmodics like Colofac usually start working within 20 minutes to an hour. However, it is vital to set realistic expectations: medication is a management tool, not a permanent cure.
My patients who see the most profound results use their medication proactively. Instead of waiting for the pain to peak, they take their medication 20 minutes before a meal they know might trigger them.
This preemptively calms the gastrocolic reflex , preventing the spasm before it even starts.
Self-care and prevention
Beyond medication, how you eat is often just as important as what you eat. Chewing your food until it is practically liquid drastically reduces the mechanical workload on your bowel.
Another clinical secret I teach my patients is to drop their shoulders and take three slow, deep belly breaths before taking their first bite of food. This simple act stimulates the vagus nerve, shifting your nervous system out of "fight or flight" and into "rest and digest" mode, which significantly reduces post-meal bloating and cramping.

