Bisphosphonates

Bisphosphonates are a class of medications primarily used to prevent and treat osteoporosis, a condition where bones become weak and fragile due to loss of bone density.

These medications work by slowing down the natural process of bone breakdown, helping to maintain bone strength and reduce the risk of fractures.

Bisphosphonates are commonly prescribed for postmenopausal women and older adults who are at increased risk of osteoporotic fractures, particularly of the hip, spine and wrist.

They may also be used to treat other conditions that affect bone health, such as Paget's disease.

How they work

These medications inhibit the activity of osteoclasts, the cells responsible for breaking down bone tissue.

By reducing bone resorption, bisphosphonates help to preserve existing bone mass and allow the body to rebuild stronger bones over time.

Treatment is typically long-term and requires regular monitoring by a healthcare professional.

Online consultation

You can access bisphosphonate treatments through an online consultation with an EU-registered doctor.

After completing a detailed medical questionnaire, a qualified physician will assess your bone health, medical history and suitability for treatment.

If approved, your prescription is sent to a certified pharmacy for discreet delivery to your door.

Understanding Bone Health and Bisphosphonates — Your GP's Guide

Bisphosphonates are medicines used to strengthen bones and reduce fracture risk in people with osteoporosis or other bone-thinning conditions. They are commonly taken as weekly or monthly tablets, or as yearly infusions.

Comprehensive Guide to Bisphosphonate Therapy

Protecting Your Bones: A Doctor's Guide to Bisphosphonates

What are bisphosphonates?

They slow the cells that break down bone, allowing bone-building cells to maintain or improve bone density. Common examples include alendronic acid, risedronate, ibandronate and zoledronic acid.

When to seek medical advice

See a GP if you have had a fragility fracture, take long-term steroids, or have a DEXA scan showing osteoporosis.

Available treatments

Alendronic acid 70 mg weekly is the most commonly prescribed in the UK. Risedronate is an alternative for those with stomach issues. IV options like zoledronic acid suit people who cannot tolerate tablets.

What to expect

Treatment is usually for five years, then reviewed. Bone protection often continues even after stopping due to long-lasting effects in bone tissue.

Self-care

Take tablets first thing in the morning with plain water, stay upright for 30 minutes, ensure adequate calcium and vitamin D, do weight-bearing exercise and avoid smoking and excess alcohol.